RAB32 Protein (AA 1-225) (His tag)
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- Target Alle RAB32 Proteine anzeigen
- RAB32 (RAB32, Member RAS Oncogene Family (RAB32))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 1-225
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RAB32 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- RAB32, 1-225aa, Human, His tag, E.coli
- Reinheit
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product RAB32 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 50% glycerol, 200mM NaCl, 2mM EDTA
- Lagerung
- 4 °C
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- Target
- RAB32 (RAB32, Member RAS Oncogene Family (RAB32))
- Andere Bezeichnung
- RAB32 (RAB32 Produkte)
- Synonyme
- cb914 Protein, hm:zehn1770 Protein, rab32 Protein, zgc:110481 Protein, MGC130912 Protein, RAB32 Protein, LOC100224194 Protein, 2810011A17Rik Protein, AU022057 Protein, RGD1559997 Protein, RAB32a, member RAS oncogene family Protein, RAB32, member RAS oncogene family Protein, RAB32, member RAS oncogene family S homeolog Protein, rab32a Protein, rab32 Protein, RAB32 Protein, rab32.S Protein, Rab32 Protein
- Hintergrund
- RAB32 belongs to the small GTPase superfamily. RAB32 modulates ER calcium handling and disrupts the specific enrichment of calnexin on the MAM (mitochondria-associated membrane), while not affecting the ER distribution of protein-disulfide isomerase and mitofusin-2. Also, RAB32 determines the targeting of PKA (cAMP-dependent protein kinase) to mitochondrial and ER membranes and through its overexpression or inactivation increases the phosphorylation of Bad and of Drp1. Through a combination of its functions as a PKA-anchoring protein and a regulator of MAM properties, the activity and expression level of RAB32 determine the speed of apoptosis onset. Recombinant human RAB32 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Ras-related protein Rab-32,. NCBI no.: NP_006825
- Molekulargewicht
- 27.6kDa (249aa), confirmed by MALDI-TOF
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