Oncostatin M Protein (OSM) (AA 26-234) (His tag)
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- Target Alle Oncostatin M (OSM) Proteine anzeigen
- Oncostatin M (OSM)
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 26-234
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses Oncostatin M Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Produktmerkmale
- OSM, 26-234aa, Human, His tag, E.coli
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product OSM Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 1mM DTT
- Lagerung
- 4 °C
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- Target
- Oncostatin M (OSM)
- Andere Bezeichnung
- OSM (OSM Produkte)
- Synonyme
- OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
- Hintergrund
- OSM, also known as Oncostatin M, is a pleiotropic cytokine that belongs to the interleukin 6 group of cytokines. Of these cytokines it most closely resembles leukemia inhibitory factor (LIF) in both structure and function. However, it is as yet poorly defined and is proving important in liver development, haematopoeisis, inflammation and possibly CNS development. It is also associated with bone formation and destruction. OSM signals through cell surface receptors that contain the protein gp130. The type I receptor is composed of gp130 and LIFR, the type II receptor is composed of gp130 and OSMR. Recombinant human OSM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Oncostatin M, MGC20461, Oncostatin M precursor. NCBI no.: NP_065391
- Molekulargewicht
- 25.9 kDa (230aa), confirmed by MALDI-TOF
- Pathways
- JAK-STAT Signalweg, Negative Regulation of Hormone Secretion
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