Iba1 Protein (AA 1-147) (His tag)

Produktnummer ABIN667414

Produktdetails

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-147

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Iba1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: AIF1, 1-147aa, Human, His tag, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200mM NaCl

Lagerung: 4 °C

Antigendetails

Target: Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))

Andere Bezeichnung: AIF1 (IBA1 Produkte)

Synonyme: AIF-1 Protein, IBA1 Protein, IRT-1 Protein, IRT1 Protein, AI607846 Protein, D17H6S50E Protein, G1 Protein, Iba1 Protein, Bart1 Protein, iba1 Protein, mrf-1 Protein, fa04b11 Protein, wu:fa04b11 Protein, AIF Protein, AIF1 Protein, aif1 Protein, allograft inflammatory factor 1 Protein, AIF1 Protein, Aif1 Protein, aif1 Protein

Hintergrund: AIF1 (Allograft inflammatory factor 1) is induced by cytokines and interferon. This protein is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. AIF1 is a cytoplasm, calcium-binding protein whose expression in transplanted human hearts correlates with rejection and development of coronary artery vasculopathy (CAV). Recombinant human AIF1, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Allograft inflammatory factor 1, AIF-1, IBA1, IRT-1, IRT1. NCBI no.: NP_001614

Molekulargewicht: 18.9kDa (167aa), confirmed by MALDI-TOF

Pathways: Smooth Muscle Cell Migration