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HUS1 Protein (AA 1-280) (His tag)

HUS1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN667288
  • Target Alle HUS1 Proteine anzeigen
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-280
    Spezies
    • 5
    • 1
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses HUS1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Produktmerkmale
    HUS1, 1-280aa, Human, His tag, E.coli
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product HUS1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 100 mM NaCl, 40% Glycerol
    Lagerung
    4 °C
  • Target
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    Andere Bezeichnung
    HUS1 (HUS1 Produkte)
    Synonyme
    hHUS1 Protein, mHus1 Protein, XHus1 Protein, hus1 Protein, HUS1 checkpoint clamp component Protein, checkpoint clamp complex protein Hus1 Protein, HUS1 checkpoint clamp component L homeolog Protein, HUS1 Protein, Hus1 Protein, hus1 Protein, hus1.L Protein
    Hintergrund
    HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex. This protein associates with Rad9 and Rad1 to form the 9-1-1(RAD9-RAD1-HUS1) complex, which localizes to DNA lesions and promotes DNA damage signaling and repair or apoptosis, cell cycle arrest. The trimeric complex is structurally similar to the proliferating cell nuclear antigen (PCNA) sliding clamp and interacts with Rad17 as a clamp-clamp loader pair during the DNA damage response. Recombinant human HUS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: checkpoint protein HUS1,. NCBI no.: NP_004498
    Molekulargewicht
    33.8 kDa (300aa), confirmed by MALDI-TOF
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