PNP Protein (AA 1-289) (His tag)

Produktnummer ABIN667267

Produktdetails

Target: PNP (NP) (Nucleoside Phosphorylase (NP))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-289

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PNP Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PNP, 1-289aa, Human, His tag, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 2mM DTT, 10% glycerol

Lagerung: 4 °C

Antigendetails

Target: PNP (NP) (Nucleoside Phosphorylase (NP))

Andere Bezeichnung: PNP (NP Produkte)

Synonyme: NP Protein, PRO1837 Protein, PUNP Protein, Np Protein, AL024301 Protein, AU015798 Protein, Np-1 Protein, Np-2 Protein, Pnp1 Protein, purine nucleoside phosphorylase Protein, purine-nucleoside phosphorylase Protein, PNP Protein, Pnp Protein

Substanzklasse: Viral Protein

Hintergrund: PNP belongs to the PNP/MTAP phosphorylase family of proteins. This protein catalyzes the reversible phosphorolysis of ribonucleosides and 2’-deoxyribonucleosides with specificity for guanine, hypoxanthine and their analogs. PNP deficiency is a rare autosomal recessive genetic disease associated with a severe defect in T-lymphocyte function and neurologic disorder in children, comprising four percent of combined immunodeficiency cases. Recombinant human PNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Purine nucleoside phosphorylase, NP, Inosine phosphorylase, PRO1837, PUNP. NCBI no.: NP_000261

Molekulargewicht: 34.2 kDa (309aa) confirmed by MALDI-TOF

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus