Retinoic Acid Receptor alpha Protein (AA 68-173) (His tag)

Produktnummer ABIN667055

Produktdetails

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 68-173

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Retinoic Acid Receptor alpha Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: RARalpha, 68-173aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 95 % by SDS-PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid in 20mM Tris pH 7.5, 0.1M NaCl, 5mM beta-mercaptoethanol

Lagerung: 4 °C

Antigendetails

Target: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Andere Bezeichnung: RARalpha (RARA Produkte)

Synonyme: NR1B1 Protein, RAR Protein, Nr1b1 Protein, RARalpha1 Protein, rar-alpha Protein, etID309833.12 Protein, rara Protein, rara2a Protein, zRAR Protein, zRAR-alpha Protein, zgc:109797 Protein, nr1b1 Protein, RAR-ALPHA1 Protein, HS-RARa Protein, fj66e06 Protein, rara2b Protein, wu:fj66e06 Protein, retinoic acid receptor alpha Protein, retinoic acid receptor, alpha Protein, retinoic acid receptor, alpha a Protein, retinoic acid receptor alpha L homeolog Protein, retinoic acid receptor, alpha b Protein, RARA Protein, Rara Protein, LOC100136372 Protein, raraa Protein, rara.L Protein, rara Protein, rarab Protein

Hintergrund: Retinoic acid receptors (RAR) belong to the large family of ligand responsive gene regulatory proteins that includes receptors for steroid and thyroid hormones. These proteins contain two highly conserved domains that are involved in determining their DNA and ligand-binding activities. Three isotypes of RARs, alpha, beta, and gamma, are encoded by distinct genetic loci and possess distinct transcriptional properties. Typically, RAR-alpha represses target gene transcription in the absence of hormone, whereas RAR-beta and gamma fail to repress under these conditions. Recombinant human RARalpha, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NR1B1, Retinoic acid receptor alpha, Retinoic acid receptor, alpha isoform 1, RAR alpha, RARalpha, RAR , Retinoic acid receptor, alpha isoform 1. NCBI no.: NP_000955

Molekulargewicht: 14 kDa (127 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteine