Diazepam Binding Inhibitor Protein (DBI) (AA 1-87) (His tag)
Kurzübersicht für Diazepam Binding Inhibitor Protein (DBI) (AA 1-87) (His tag) (ABIN667004)
Target
Alle Diazepam Binding Inhibitor (DBI) Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- AA 1-87
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Aufreinigungstag / Konjugat
- Dieses Diazepam Binding Inhibitor Protein ist gelabelt mit His tag.
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Sequenz
- MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF TGKAKWDAWN ELKGTSKEDA MKAYINKVEE LKKKYGI
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Produktmerkmale
- ACBP, 1-87aa, Human, His tag, E.coli
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Aufreinigung
- > 95% by SDS-PAGE
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 20 mM Tris-HCl buffer ( pH 8.0) containing 0.1M NaCl, 10 % glycerol
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- Diazepam Binding Inhibitor (DBI)
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Andere Bezeichnung
- ACBP/DBI
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Hintergrund
- ACBP, also known as ACBD1, is a diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Expression of ACBP is significantly induced during adipocyte differentiation. ACBP is a target for proliferator-activated receptor (PPAR) gamma, and is directly activated by PPARgamma/RXRalpha and PPARalpha/RXRalpha, but not by PPARdelta/RXRalpha. Recombinant human ACBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
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Molekulargewicht
- 12.2 kDa (107aa) confirmed by MALDI-TOF
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NCBI Accession
- NP_001073331
Target
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