Diazepam Binding Inhibitor Protein (DBI) (AA 1-87) (His tag)

Produktnummer ABIN667004

Dieses Recombinant Diazepam Binding Inhibitor-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Diazepam Binding Inhibitor Protein (DBI) (AA 1-87) (His tag) (ABIN667004)

Target: Diazepam Binding Inhibitor (DBI)

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: SDS-PAGE (SDS)

Reinheit: > 95 %

Produktdetails

Proteineigenschaft: AA 1-87

Aufreinigungstag / Konjugat: Dieses Diazepam Binding Inhibitor Protein ist gelabelt mit His tag.

Sequenz: MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF TGKAKWDAWN ELKGTSKEDA MKAYINKVEE LKKKYGI

Produktmerkmale: ACBP, 1-87aa, Human, His tag, E.coli

Aufreinigung: > 95% by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 20 mM Tris-HCl buffer ( pH 8.0) containing 0.1M NaCl, 10 % glycerol

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Antigendetails

Target: Diazepam Binding Inhibitor (DBI)

Andere Bezeichnung: ACBP/DBI

Hintergrund: ACBP, also known as ACBD1, is a diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. Expression of ACBP is significantly induced during adipocyte differentiation. ACBP is a target for proliferator-activated receptor (PPAR) gamma, and is directly activated by PPARgamma/RXRalpha and PPARalpha/RXRalpha, but not by PPARdelta/RXRalpha. Recombinant human ACBP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Molekulargewicht: 12.2 kDa (107aa) confirmed by MALDI-TOF

NCBI Accession: NP_001073331