NDRG1 Protein (AA 1-394) (His tag)

Produktnummer ABIN666891

Produktdetails

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-394

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NDRG1 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: NDRG1, 1-394 aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1 mM PMSF, 10% Glycerol

Lagerung: 4 °C

Antigendetails

Target: NDRG1 (N-Myc Downstream Regulated 1 (NDRG1))

Andere Bezeichnung: NDRG1 (NDRG1 Produkte)

Synonyme: CAP43 Protein, CMT4D Protein, DRG-1 Protein, DRG1 Protein, GC4 Protein, HMSNL Protein, NDR1 Protein, NMSL Protein, PROXY1 Protein, RIT42 Protein, RTP Protein, TARG1 Protein, TDD5 Protein, Ndr1 Protein, Ndrl Protein, cap43 Protein, cmt4d Protein, drg1 Protein, gc4 Protein, hmsnl Protein, ndr1 Protein, ndrg1 Protein, nmsl Protein, proxy1 Protein, rit42 Protein, rtp Protein, targ1 Protein, tdd5 Protein, xndrg1 Protein, ndrg4 Protein, cb775 Protein, wu:fb60h02 Protein, zgc:63944 Protein, NDRG1 Protein, NON-RACE SPECIFIC DISEASE RESISTANCE PROTEIN Protein, non race-specific disease resistance 1 Protein, ndrg1-a Protein, ndrg1-b Protein, xNDRG1-A Protein, ndrg1l Protein, zgc:73047 Protein, N-myc downstream regulated 1 Protein, N-myc downstream regulated gene 1 Protein, N-myc downstream regulated 1 S homeolog Protein, N-myc downstream regulated 1a Protein, Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family Protein, N-myc downstream regulated 1 L homeolog Protein, N-myc downstream regulated 1b Protein, NDRG1 Protein, Ndrg1 Protein, ndrg1.S Protein, ndrg1 Protein, ndrg1a Protein, NDR1 Protein, ndrg1.L Protein, ndrg1b Protein

Hintergrund: N-myc downstream regulated gene (NDRG)-1 is one of 4 members of the NDRG alpha/beta-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease. Recombinant human NDRG1, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: CAP43, CMT4D, DRG1, GC4, HMSNL, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5, N-myc downstream regulated 1 TDD5, 42 kDa, anti-GC4, cmt4d, Differentiation related gene1 protein, Drg 1, hmsnl, Human mRNA for RTP complete cds, NDRG1, tdds, N myc downstream regulated gene 1, N myc downstream regulated gene 1 protein, Ndr 1, ndr1, NDRG 1, NDRG1 protein, Protein nickel specific induction protein, Nickel specific induction protein Cap43, nmsl, Nmyc downstream regulated, reduced in tumor, reducin, Nmyc downstream regulated gene1, Nmyc downstream regulated gene1 protein, Protein regulated by oxygen 1, Protein regulated by oxygen1, proxy1, Reducing agents and tunicamycin responsive protein, tunicamycin-responsive protein. NCBI no.: NP_006087

Molekulargewicht: 43.9 kDa (402aa), confirmed by MALDI-TOF.