PSMA7 Protein (AA 1-248) (His tag)

Produktnummer ABIN666877

Produktdetails

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-248

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PSMA7 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Produktmerkmale: PSMA7, 1-248aa, Human, His-tagged, Recombinant, E.coli

Reinheit: > 90 % by SDS - PAGE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl

Lagerung: 4 °C

Antigendetails

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Andere Bezeichnung: PSMA7 (PSMA7 Produkte)

Synonyme: C6 Protein, HSPC Protein, RC6-1 Protein, XAPC7 Protein, C6-I Protein, DDBDRAFT_0185059 Protein, DDBDRAFT_0217080 Protein, DDB_0185059 Protein, DDB_0217080 Protein, hspc Protein, rc6-1 Protein, xapc7 Protein, psma7 Protein, psma4-B Protein, proteasome subunit alpha 7 Protein, proteasome (prosome, macropain) subunit, alpha type 7 Protein, 20S proteasome subunit alpha-7 Protein, proteasome subunit alpha 7 S homeolog Protein, proteasome subunit alpha 7 L homeolog Protein, PSMA7 Protein, Psma7 Protein, psmA7 Protein, psma7 Protein, psma7.S Protein, psma7.L Protein

Hintergrund: Proteasome alpha 7, PSMA7, is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. PSMA7, belonged to the peptidase T1A family, is a 20S core alpha subunit of proteasome. This protein was found to interact specifically with two subdomains of HIF-1alpha and inhibited the transactivation function of HIF-1alpha under both normoxic and hypoxia-mimicking conditions. Recombinant PSMA7 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: C6, HSPC, MGC3755, RC6-1, XAPC7, Proteasome alpha 7 subunit, PSMA7 , Proteasome alpha 7 subunit Proteasome (prosome macropain) subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, PSMA 7, RC6 1, Proteasome subunit RC6 1, Proteasome subunit XAPC7. NCBI no.: NP_002783

Molekulargewicht: 30.0 kDa (268 aa), confirmed by MALDI-TOF.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA