PIK3R1 Protein

Name: PIK3R1

Hergestellt in: Insektenzellen

Produktnummer: ABIN629460

Produktbeschreibung

Gen-ID: 5295

Swiss-Prot: NM_181523

Beschreibung: The PI3K comprises of a 110 kDa catalytic subunit and a 85 kDa regulatory subunit. A number of isoforms of the 110 kDa catalytic subunit and the 85 kDa regulatory subunit exist in cells. p85alphamodulates the interaction between PI3K and platelet-derived growth factor receptor (1). Furthermore, estrogen receptor isoform ER-alpha binds in a ligand-dependent manner to the p85alpha regulatory subunit of PI3K. Stimulation with estrogen increases ER-alpha-associated PI3K activity, leading to the activation of protein kinase B/AKT and endothelial nitric oxide synthase (eNOS) (2).

Molekulargewicht: 86.0 kDa

Anwendungen

Konzentration: 0.2 mg/ml

Reinheit: >=95%

Lagerung: Long term Storage: -80°C. Shipping condition: dry ice. Shelf Life: 12 months.

Beschränkungen: Nur für Forschungszwecke einsetzbar