Histone Deacetylase 8 (HDAC8) Protein

Name: Histone Deacetylase 8 (HDAC8)

Synonyme: RPD3, HDACL1, 2610007D20Rik, RGD1562895, zgc:66196, wu:fd19a02, MGC80565, hdac8, HDAC8, MGC142318, ATHDA8, HDA08, HDA8, histone deacetylase 8, HISTONE DEACETYLASE 8, T27G7.14, T27G7_14

Hergestellt in: Insektenzellen

Herkunft (Gen): Human

Produktnummer: ABIN629458

Produktbeschreibung

Gen-ID: 55869

Swiss-Prot: Q9BY41

Beschreibung: Human Histone Deacetylase 8 (HDAC8) is a member of the class I Histone Deacetylases. HDACs are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells. HDACs catalyze the removal of acetyl groups from lysines near the N-termini of histones. Human HDACs have been implicated in a variety of human diseases such as cardiomyopathy, osteodystrophy, neurodegenerative disorders, aging and cancer. Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation. Like other class I and II HDAC members, the activity of HDAC8 is sensitive to HDAC inhibitor Trichostatin A (TSA).

Molekulargewicht: 44 kDa

Anwendungen

Reinheit: >=90%

Lagerung: Long term Storage: -80°C. Shipping condition: gel pack. Shelf Life: 12 months.

Forschungsgebiet: Kardiovaskuläres System, Hypertrophie, Krebs, Transkriptionsfaktoren, DNS/RNS

Beschränkungen: Nur für Forschungszwecke einsetzbar