Heme Oxygenase (Decycling) 1 (HMOX1) Protein

Name: Heme Oxygenase (Decycling) 1 (HMOX1)

Synonyme: HO1, HO-1, Hmox, Hemox, Hsp32, D8Wsu38e, Ho1, Heox, Ho-1, HEOXG, hsp32, HMOX1, MGC132176, zgc:65984, ARABIDOPSIS THALIANA HEME OXYGENASE 1, ATHO1, F18A8.4, F18A8_4, GENOMES UNCOUPLED 2, GUN2, HEME OXYGENASE, HEME OXYGENASE 1, HEME OXYGENASE 6, HY6, PLASTID HEME OXYGENASE, REVERSAL OF THE DET PHENOTYPE 4, TED4, Hmox1, DKFZp469G141

Protein-Typ: Recombinant

Herkunft (Gen): Human

Produktnummer: ABIN623592

Produktbeschreibung

Produktmerkmale: Recombinant Human Heme Oxygenase 1

Sequenz: MERPQPHSMP QDLSEALKEA TKEVHTQAEN AEFMRNFQKG QVTRDGFKLV MASLYHIYVA LEEEIERNKE SPVFAPVYFP EELHRKAALEQDLAFWYGPR WQEVIPYTPA MQRYVKRLHE VGRTEPELLV AHAYTRYLGD LSGGQVLKKI AQKALDLPSS GEGLAFFTFP NIASATKFKQLYRSRMNSLE MTPAVRQRVI EEAKTAFLLN IQLFEELQEL LTHDTKDQSP SRAPGLRQRA SNKVQDSAPV ETPRGKPPLN TRSQAPLEHHHHHH.

Format: Liquid

Beschreibung: HO-1 Human Recombinant protein produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 274 amino acids (1-266) and having a molecular mass of 31.4 kDa. HO-1 is fused to 8 amino acid His Tag at C-Terminus and purified by proprietary chromatographic techniques. Introduction: HMOX1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is then converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HMOX1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme Oxygenase-1 is involved in the regulation of cardiovascular function and its adaptive response to a variety of stressors. HMOX1 is induced in the colon of ulcerative colitis. HMOX1 is found to overexpress with a higher extent of intraplaque angiogenesis implies a multi-faceted role for HMOX1 in modulating the progression of atherosclerosis. HMOX1 expression reduced LPS-stimulated secretion of MCP-1, IL-6, IL-10, and TNF-alpha in murine and human macrophages. Synonyms: HO-1, HSP32, bK286B10, HMOX-1, Heme oxygenase 1, HMOX1, HO, HO1.

Synonyme: HO1, HO-1, Hmox, Hemox, Hsp32, D8Wsu38e, Ho1, Heox, Ho-1, HEOXG, hsp32, HMOX1, MGC132176, zgc:65984, ARABIDOPSIS THALIANA HEME OXYGENASE 1, ATHO1, F18A8.4, F18A8_4, GENOMES UNCOUPLED 2, GUN2, HEME OXYGENASE, HEME OXYGENASE 1, HEME OXYGENASE 6, HY6, PLASTID HEME OXYGENASE, REVERSAL OF THE DET PHENOTYPE 4, TED4, Hmox1, DKFZp469G141

Anwendungen

Reinheit: Greater than 95.0% as determined by SDS-PAGE.

Buffer: HMOX1 solution containing 20mM Tris pH-8, 50mM NaCl, 0.1mM PMSF and 10% glycerol.

Lagerung: HMOX1 Human Recombinant although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar