MYLIP Protein (AA 1-445, full length) (His tag)
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- Target Alle MYLIP Proteine anzeigen
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- full length, AA 1-445
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Spezies
- Human
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Quelle
- Hefe
- Aufreinigungstag / Konjugat
- Dieses MYLIP Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Sequenz
- MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLL CSPEQAVELS ALLAQTKFGD YNQNTAKYNY EELCAKELSS ATLNSIVAKH KELEGTSQAS AEYQVLQIVS AMENYGIEWH SVRDSEGQKL LIGVGPEGIS ICKDDFSPIN RIAYPVVQMA TQSGKNVYLT VTKESGNSIV LLFKMISTRA ASGLYRAITE THAFYRCDTV TSAVMMQYSR DLKGHLASLF LNENINLGKK YVFDIKRTSK EVYDHARRAL YNAGVVDLVS RNNQSPSHSP LKSSESSMNC SSCEGLSCQQ TRVLQEKLRK LKEAMLCMVC CEEEINSTFC PCGHTVCCES CAAQLQSCPV CRSRVEHVQH VYLPTHTSLL NLTVI
- Aufreinigung
- SDS-PAGE
- Reinheit
- > 90 %
- Top Product
- Discover our top product MYLIP Protein
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Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) protein (GST tag)
MYLIP Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) protein (Strep Tag)Crystallography grade MYLIP Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) protein (Strep Tag)Crystallography grade MYLIP Spezies: Maus Wirt: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445), (full length) protein (GST tag)MYLIP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % SDS
Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445), (full length) protein (His tag)MYLIP Spezies: Human Wirt: Hefe Recombinant > 90 % SDS
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Lagerung
- -80 °C,4 °C,-20 °C
- Informationen zur Lagerung
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
- Andere Bezeichnung
- MYLIP (MYLIP Produkte)
- Synonyme
- IDOL Protein, MIR Protein, 9430057C20Rik Protein, Mir Protein, mylip Protein, wu:fj36b03 Protein, zgc:55987 Protein, MYLIP Protein, mir Protein, zgc:153767 Protein, myosin regulatory light chain interacting protein Protein, myosin regulatory light chain interacting protein a Protein, myosin regulatory light chain interacting protein L homeolog Protein, myosin regulatory light chain interacting protein b Protein, MYLIP Protein, Mylip Protein, mylipa Protein, mylip.L Protein, mylip Protein, mylipb Protein
- Hintergrund
- E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
- Molekulargewicht
- 51.9 kDa
- UniProt
- Q8WY64
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