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TNFSF18 Protein (AA 47-173) (Fc Tag)

TNFSF18 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Produktnummer ABIN4949171
  • Target Alle TNFSF18 Proteine anzeigen
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 47-173
    Spezies
    • 27
    • 6
    • 1
    Maus
    Quelle
    • 18
    • 10
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TNFSF18 Protein ist gelabelt mit Fc Tag.
    Applikation
    Functional Studies (Func)
    Sequenz
    AA 47-173
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 41.4 kDa. As a result of glycosylation, the protein migrates as 45 kDa under reducing (R) condition, and 80-100 kDa under non-reducing (NR) condition (SDS-PAGE).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product TNFSF18 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
  • Target
    TNFSF18 (Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18))
    Andere Bezeichnung
    GITR Ligand (TNFSF18 Produkte)
    Synonyme
    Gitrl Protein, AITRL Protein, GITRL Protein, TL6 Protein, hGITRL Protein, TNLG2A Protein, tumor necrosis factor (ligand) superfamily, member 18 Protein, TNF superfamily member 18 Protein, Tnfsf18 Protein, TNFSF18 Protein
    Hintergrund
    Tumor necrosis factor ligand superfamily member 18 (TNFSF18) is also known as Glucocorticoid - induced TNF-related ligand (GITRL or GITR Ligand), Activation - inducible TNF - related ligand (AITRL), which belongs to the tumor necrosis factor family. TNFSF18 is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 / GITRL is up-regulated after stimulation by bacterial lipopolysaccharides (LPS). TNFSF18 Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. TNFSF18 / GITR Ligand is important for interactions between activated T-lymphocytes and endothelial cells. TNFSF18 also mediates activation of NF-kappa-B.
    Molekulargewicht
    41.4 kDa
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