Kallikrein Protein

Name: Kallikrein

Synonyme: klkr, kallikrein, KLK1E2, hpk

Herkunft (Gen): Human

Produktnummer: ABIN491202

Produktbeschreibung

Gen-ID: 3816

Swiss-Prot: P06870

Format: Frozen

Beschreibung: Kallikrein, Human Plasma. Activation of Prekallikrein with Factor alpha-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is >95% by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol. Prepared from plasma found negative by FDA accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).

Molekulargewicht: 86000

Anwendungen

Konzentration: Sample concentration 2.0 mg/ml, concentration varies by lot

Reinheit: >95% by SDS-PAGE

Reinigung: Chromatographically purified

Buffer: 0.004M Sodium Acetate, 0.15M NaCl, pH 5.3

Lagerung: Store at -70°C

Forschungsgebiet: Gerinnung