Aprotinin (Active) Protein

Details zu Produkt Nr. ABIN413899, Anbieter: Anmelden zum Anzeigen
Proteinname
  • BPI
  • BPTI
  • pancreatic trypsin inhibitor-like
  • pancreatic trypsin inhibitor
  • LOC100158011
  • PTI
Spezies
Rind (Kuh)
6
Quelle
Cow
3
1
Protein-Typ
Native
Biologische Aktivität
Active
Applikation
Functional Studies (Func), SDS-PAGE (SDS), Western Blotting (WB)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Verwendungszweck >98% Pure active Aprotinin.
Produktmerkmale Protein Source: Bovine lung
Reinheit SDS-PAGE: ≥98 %
HPLC: ≥98 %
Sterilität Sterile filtered
Endotoxin-Niveau <0.1 ng/μg
Hintergrund Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. It is present in blood and in most tissues, with a high concentration in lung, inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins. Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512 Daltons. Aprotinin is purified by proprietary chromatographic techniques.
Alternate Names: Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP
Molekulargewicht 6.5 kDa
Applikationshinweise Optimal working dilution should be determined by the investigator.
Kommentare

Biological Activity: 5 x 10⁶ IU/mg.
Activity Results: 6 x 10⁶ IU/mg.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute in H₂O to a concentration of 1 mg/mL. The solution can then be diluted into other aqueous buffers and store at 4 °C for 1 week or -20 °C for future use. For long-term storage, it is recommend to add a carrier protein (e.g., 0.1 % BSA). Prevent freeze/thaw cycles.
Buffer Sterile filtered and lyophilized with no additives
Konservierungsmittel Without preservative
Handhabung Centrifuge the vial prior to opening.
Lagerung -20 °C
Informationen zur Lagerung -20°C
Haltbarkeit 12 months
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