D4-GDI Protein

Name: D4-GDI

Synonyme: ARHGDIB

Protein-Typ: Recombinant

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Applikation: Western Blot (WB), ELISA, Funktionale Studien (Func)

Produktnummer: ABIN413175

Produktbeschreibung

Beschreibung: D4-GDI belongs to the family of rho-GDI or GDP-dissociation inhibitors for the Rho/Rac family of small G proteins, consisting of rhoGDI-1, D4-GDI/rhoGDI-2 and rhoGDI-3. It inhibits the release of GDP from the Rho proteins, essential for GTP-loading and activation of GTPase activity. D4-GDI is located in the cytoplasm and is involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas-mediated apoptosis.

Molekulargewicht: 54 kDa

Anwendungen

Reinheit: > 90% as determined by SDS-PAGE and HPLC. ENDOTOXIN: Endotoxin level is less than 0.1 ng/mg of D4-GDI PHYSICAL

Buffer: 100µg/ml in 50mM Tris-Acetate, pH 7.5, 1mM EDTA, 20% Glycerol.

Lagerung: Stable at –20 °C or –80 ο C. Stable for 6-12 months. Avoid freeze-thaw cycles.

Beschränkungen: Nur für Forschungszwecke einsetzbar