PARP3 Protein (HA tag,His tag)
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- Target Alle PARP3 Proteine anzeigen
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Spezies
- Human
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Quelle
- Insect cells (Sf21)
- Aufreinigungstag / Konjugat
- Dieses PARP3 Protein ist gelabelt mit HA tag,His tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag.
- Reinheit
- >98 % (SDS-PAGE)
- Top Product
- Discover our top product PARP3 Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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>10U/mg protein (only monoADP-ribosyl transferase activity).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In 50 mM TRIS-HCl, pH 7.5, containing 100 mM sodium chloride and 50 mM imidazole, 0.2 % NP-40 and 10 % glycerol.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - Haltbarkeit
- 6 months
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- Target
- PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))
- Andere Bezeichnung
- PARP-3 [ARTD3] (PARP3 Produkte)
- Synonyme
- ADPRT-3 Protein, PARP-3 Protein, PM38 Protein, Adprtl3 Protein, fj17c06 Protein, wu:fj17c06 Protein, zgc:66157 Protein, PARP3 Protein, parp3 Protein, ADPRT3 Protein, ADPRTL2 Protein, ADPRTL3 Protein, ARTD3 Protein, IRT1 Protein, PADPRT-3 Protein, A930002C11Rik Protein, AW990611 Protein, Adprt3 Protein, pADPRT-3 Protein, seed maturation protein PM38 Protein, poly (ADP-ribose) polymerase family, member 3 Protein, poly(ADP-ribose) polymerase family member 3 Protein, poly(ADP-ribose) polymerase family member 3 L homeolog Protein, PARP3 Protein, parp3 Protein, parp3.L Protein, Parp3 Protein
- Hintergrund
- PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
- UniProt
- Q9Y6F1
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