NAPRT1 Protein (His tag)
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- Target Alle NAPRT1 (NAPRT) Proteine anzeigen
- NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses NAPRT1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Kreuzreaktivität
- Human
- Produktmerkmale
- Human NAPRTase is fused at the N-terminus to a His-tag.
- Reinheit
- >98 % (SDS-PAGE)
- Top Product
- Discover our top product NAPRT Protein
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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~0.27 U/mg protein. One unit is defined as the amount of enzyme that synthesizes 1μmol nicotinic acid mononucleotide (NaMN) per min.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- In 50 mM HEPES/KOH pH 7.5 containing 300 mM potassium chloride and 10 mM DTT.
- Konservierungsmittel
- Dithiothreitol (DTT)
- Vorsichtsmaßnahmen
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
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Short Term Storage: -20°C
Long Term Storage: -80°C
Stable for at least 6 months after receipt when stored at -80°C. - Haltbarkeit
- 6 months
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- Target
- NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))
- Andere Bezeichnung
- NAPRTase (NAPRT Produkte)
- Synonyme
- PP3856 Protein, 9130210N20Rik Protein, zgc:77870 Protein, nicotinate phosphoribosyltransferase Protein, NAPRT Protein, Naprt Protein, naprt Protein
- Hintergrund
- Human nicotinate phosphoribosyltransferase (NAPRTase) is localized in the cytoplasm and is involved in biological processes such as NAD biosynthetic and metabolic processes, nicotinamide metabolic process, nicotinate nucleotide salvage, response to oxidative stress and water-soluble vitamin metabolic process. It functions by catalyzing the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN) and is essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. It is a crucial factor in the NAD+ biosynthesis pathway. Catalytic activity: Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate.
- Molekulargewicht
- ~58.0kDa
- UniProt
- Q6XQN6
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