TJP3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2733730

Produktdetails

Target: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TJP3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Tight junction protein 3 (zona occludens 3) (TJP3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Abstract: TJP3 Produkte

Synonyme: cb766 Protein, wu:fj93c08 Protein, zo-3 Protein, zo3 Protein, ZO-3 Protein, ZO3 Protein, tight junction protein 3 Protein, tight junction protein 3 S homeolog Protein, tjp3 Protein, tjp3.S Protein, TJP3 Protein, Tjp3 Protein

Hintergrund: The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.

Molekulargewicht: 104.6 kDa

NCBI Accession: NP_055243