RING1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730932

Produktdetails

Target: RING1 (Ring Finger Protein 1 (RING1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RING1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RING1 / RNF1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RING1 (Ring Finger Protein 1 (RING1))

Andere Bezeichnung: Ring1,rnf1 (RING1 Produkte)

Synonyme: RING1A Protein, RNF1 Protein, Ring1A Protein, bap-1 Protein, bap1 Protein, ding Protein, hipi3 Protein, ring1a Protein, ring1b Protein, ring2 Protein, rnf1 Protein, rnf2-a Protein, ring1 Protein, ring1b-B Protein, rnf2-b Protein, ring finger protein 1 Protein, ring finger protein 1 S homeolog Protein, ring finger protein 1 L homeolog Protein, RING1 Protein, Ring1 Protein, ring1.S Protein, ring1.L Protein

Hintergrund: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Molekulargewicht: 42.2 kDa

NCBI Accession: NP_002922