RBM8A Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730625

Produktdetails

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses RBM8A Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human RBM8A / RBM8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: RBM8A (RNA Binding Motif Protein 8A (RBM8A))

Andere Bezeichnung: Rbm8a,rbm8 (RBM8A Produkte)

Synonyme: BOV-1A Protein, BOV-1B Protein, BOV-1C Protein, C1DELq21.1 Protein, DEL1q21.1 Protein, MDS014 Protein, RBM8 Protein, RBM8B Protein, TAR Protein, Y14 Protein, ZNRP Protein, ZRNP1 Protein, 2310057C03Rik Protein, AA673428 Protein, Rbm8 Protein, RBM8A Protein, rbm8 Protein, rbm8a Protein, rnp-5 Protein, fb34f03 Protein, wu:fb34f03 Protein, zgc:110525 Protein, rbm8-A Protein, rbm8a-A Protein, rbm8-B Protein, RNA binding motif protein 8A Protein, RNA binding motif protein 8a Protein, RNA binding motif protein 8A S homeolog Protein, RNA binding motif protein 8A L homeolog Protein, RBM8A Protein, Rbm8a Protein, rbm8a Protein, rbm8a.S Protein, rbm8a.L Protein

Hintergrund: This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.

Molekulargewicht: 19.7 kDa

NCBI Accession: NP_005096