RAD18 Protein (Myc-DYKDDDDK Tag)
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- Target Alle RAD18 Proteine anzeigen
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- HEK-293 Cells
- Aufreinigungstag / Konjugat
- Dieses RAD18 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
- Applikation
- Antibody Production (AbP), Standard (STD)
- Produktmerkmale
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- Recombinant human RAD18 / RNF73 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Reinheit
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAD18 Protein
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- Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Kommentare
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The tag is located at the C-terminal.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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USP7 is essential for maintaining Rad18 stability and DNA damage tolerance." in: Oncogene, Vol. 35, Issue 8, pp. 965-76, (2016) (PubMed).
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USP7 is essential for maintaining Rad18 stability and DNA damage tolerance." in: Oncogene, Vol. 35, Issue 8, pp. 965-76, (2016) (PubMed).
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- Target
- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
- Andere Bezeichnung
- Rad18,rnf73 (RAD18 Produkte)
- Synonyme
- RNF73 Protein, 2810024C04Rik Protein, Rad18sc Protein, zgc:55577 Protein, RAD18 Protein, DDBDRAFT_0218120 Protein, DDBDRAFT_0304878 Protein, DDB_0218120 Protein, DDB_0304878 Protein, DKFZp469H0810 Protein, RAD18, E3 ubiquitin protein ligase Protein, RAD18 E3 ubiquitin protein ligase Protein, E3 ubiquitin-protein ligase RAD18 Protein, E3 ubiquitin-protein ligase Protein, DNA repair protein and ATPase Protein, C3HC4-type zinc finger-containing protein Protein, RAD18 Protein, Rad18 Protein, rad18 Protein
- Hintergrund
- The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
- Molekulargewicht
- 56 kDa
- NCBI Accession
- NP_064550
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