PTPN18 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2730112

Produktdetails

Target: PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PTPN18 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PTPN18 / BDP1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))

Andere Bezeichnung: Ptpn18,bdp1 (PTPN18 Produkte)

Synonyme: BDP1 Protein, PTP-HSCF Protein, FLP1 Protein, HSCF Protein, PTP-K1 Protein, Ptpk1 Protein, PTP20 Protein, protein tyrosine phosphatase, non-receptor type 18 Protein, PTPN18 Protein, Ptpn18 Protein

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 50.3 kDa

NCBI Accession: NP_055184