PKN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2729066

Produktdetails

Target: PKN1 (Protein Kinase N1 (PKN1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses PKN1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human PKN1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: PKN1 (Protein Kinase N1 (PKN1))

Andere Bezeichnung: Pkn1 (PKN1 Produkte)

Synonyme: DBK Protein, PAK-1 Protein, PAK1 Protein, PKN Protein, PKN-ALPHA Protein, PRK1 Protein, PRKCL1 Protein, F730027O18Rik Protein, Pkn Protein, Prkcl1 Protein, Stk3 Protein, PKN1 Protein, 3-2 Protein, CG2049 Protein, CG2055 Protein, CT6637 Protein, CT6660 Protein, DPKN Protein, Dmel\\CG2049 Protein, Dpkn Protein, PRK2 Protein, Pk45C Protein, Pk?3 Protein, dPKN Protein, l(2)06736 Protein, l(2)45Ca Protein, v(2)rG232 Protein, protein kinase N1 Protein, protein kinase N1b Protein, Protein kinase N Protein, PKN1 Protein, Pkn1 Protein, pkn1b Protein, pkn1 Protein, Pkn Protein

Hintergrund: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Molekulargewicht: 103.8 kDa

NCBI Accession: NP_002732