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Beclin 1 Protein (Myc-DYKDDDDK Tag)

BECN1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715218
  • Target Alle Beclin 1 (BECN1) Proteine anzeigen
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    Protein-Typ
    Recombinant
    Spezies
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 5
    • 5
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses Beclin 1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Beclin-1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BECN1 Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Zhu, Messer, Wang, Lin, Cham, Chang, Billiar, Lotze, Boone, Chang: "Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation." in: The Journal of clinical investigation, Vol. 125, Issue 3, pp. 1098-110, (2015) (PubMed).

  • Target
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    Andere Bezeichnung
    Beclin-1 (BECN1 Produkte)
    Synonyme
    beclin-1 Protein, atg6 Protein, vps30 Protein, beclin1 Protein, Beclin-1 Protein, becn1 Protein, zgc:73097 Protein, ATG6 Protein, VPS30 Protein, 4921513J16Rik Protein, 5430417M23Rik Protein, Atg6 Protein, beclin 1 Protein, beclin 1, autophagy related Protein, beclin 1 protein Protein, beclin-1 Protein, beclin family protein Protein, beclin 1, autophagy related L homeolog Protein, BECN1 Protein, becn1 Protein, atg6 Protein, CpipJ_CPIJ011087 Protein, PTRG_07825 Protein, SJAG_01876 Protein, Becn1 Protein, becn1.L Protein
    Hintergrund
    This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    51.7 kDa
    NCBI Accession
    NP_003757
    Pathways
    Autophagie
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