ALDH2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714541

Produktdetails

Target: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ALDH2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ALDH2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Andere Bezeichnung: Aldh2 (ALDH2 Produkte)

Synonyme: aldh2 Protein, aldh2a Protein, zgc:63786 Protein, MGC80785 Protein, aldh-e2 Protein, aldhi Protein, aldm Protein, rf2b Protein, ALDH-E2 Protein, ALDHI Protein, ALDM Protein, Ahd-5 Protein, Ahd5 Protein, aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 Protein, aldehyde dehydrogenase 2 family (mitochondrial) L homeolog Protein, aldehyde dehydrogenase 2 family (mitochondrial) Protein, aldehyde dehydrogenase 2 Protein, aldehyde dehydrogenase Protein, aldehyde dehydrogenase (NAD(+)) Protein, hypothetical protein Protein, aldehyde dehydrogenase 2, mitochondrial Protein, aldh2.1 Protein, aldh2.L Protein, aldh2 Protein, ALDH2 Protein, RHA1_RS43090 Protein, aldH2 Protein, OE_RS03015 Protein, Aldh2 Protein

Hintergrund: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]

Molekulargewicht: 54.4 kDa

NCBI Accession: NP_000681