CHMP4B Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713984

Produktdetails

Target: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CHMP4B Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CHMP4B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Andere Bezeichnung: Chmp4b (CHMP4B Produkte)

Synonyme: C20orf178 Protein, CHMP4A Protein, CTPP3 Protein, CTRCT31 Protein, SNF7 Protein, SNF7-2 Protein, Shax1 Protein, VPS32B Protein, Vps32-2 Protein, dJ553F4.4 Protein, 2010012F05Rik Protein, C76846 Protein, Snf7-2 Protein, RGD1309846 Protein, RGD1565889 Protein, CHMP4b Protein, chmp4b Protein, chmp4b.S Protein, CHMP4c Protein, c20orf178 Protein, wu:fc96b02 Protein, zgc:55566 Protein, charged multivesicular body protein 4B Protein, charged multivesicular body protein 4Ba Protein, charged multivesicular body protein 4B L homeolog Protein, charged multivesicular body protein 4Bb Protein, CHMP4B Protein, Chmp4b Protein, chmp4ba Protein, chmp4b.L Protein, chmp4bb Protein

Hintergrund: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009].

Molekulargewicht: 24.8 kDa

NCBI Accession: NP_789782