Keratin 16 (KRT16) protein (His tag)

Details zu Produkt Nr. ABIN2712823, Anbieter: Anmelden zum Anzeigen
Proteinname
  • KRT17
  • krt16
  • CK16
  • FNEPPK
  • K16
  • K1CP
  • KRT16A
  • NEPPK
  • AI324768
  • Krt1-16
  • Ka16
  • keratin 17
  • keratin 16
  • keratin 16 (focal non-epidermolytic palmoplantar keratoderma)
  • KRT17
  • KRT16
  • Krt16
  • krt16
Spezies
Human
6
1
Quelle
Escherichia coli (E. coli)
3
2
2
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
His tag
Applikation
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Spezifität Optimal preservation of protein structure, post-translational modifications and functions.
Produktmerkmale
  • Recombinant human Cytokeratin 16 (full length, N-term HIS tag) protein expressed in E. coli.
  • Produced with end-sequenced ORF clone
Reinheit > 80 % as determined by SDS-PAGE and Coomassie blue staining
Hintergrund The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.
Molekulargewicht 51.3 kDa
NCBI Accession NP_005548
Forschungsgebiet Signaling, Extracellular Matrix, Cytokeratins, Cytoskeleton
Applikationshinweise Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Kommentare

The tag is located at the N-terminal.

Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration > 50 μg/mL
Buffer 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Lagerung -80 °C
Informationen zur Lagerung Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Bilder des Herstellers
Western Blotting (WB) image for Keratin 16 (KRT16) protein (His tag) (ABIN2712823) Validation with Western Blot