HSA Protein (AA 25-609) (His tag)

Produktnummer ABIN2181228

Produktdetails

Target: HSA (Human Serum Albumin (HSA))

Protein-Typ: Recombinant

Proteineigenschaft: AA 25-609

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses HSA Protein ist gelabelt mit His tag.

Sequenz: AA 25-609

Produktmerkmale: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.3 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: PBS, pH 7.4

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Referenzen

Siaw, Raghunath, Dyer: "Peripheral Protein Unfolding Drives Membrane Bending." in: Langmuir : the ACS journal of surfaces and colloids, Vol. 34, Issue 28, pp. 8400-8407, (2019) (PubMed).

Happonen, Hauri, Svensson Birkedal, Karlsson, de Neergaard, Khakzad, Nordenfelt, Wikström, Wisniewska, Björck, Malmström, Malmström: "A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies." in: Nature communications, Vol. 10, Issue 1, pp. 2727, (2019) (PubMed).

Antigendetails

Target: HSA (Human Serum Albumin (HSA))

Andere Bezeichnung: HSA (HSA Produkte)

Synonyme: PRO0883 Protein, PRO0903 Protein, PRO1341 Protein, albumin Protein, ALB Protein

Hintergrund: Serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80 % of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

Molekulargewicht: 67.4 kDa

NCBI Accession: NP_000468