Interleukin 6 (IL6) (AA 29-212) (Active) Protein

Details zu Produkt Nr. ABIN2009972, Anbieter: Anmelden zum Anzeigen
Proteinname
  • Il-6
  • ILg6
  • Ifnb2
  • BSF2
  • HGF
  • HSF
  • IFNB2
  • IL-6
  • CHIL-6
  • il6
  • interleukin 6
  • interleukin 6 (interferon, beta 2)
  • interleukin-6
  • Il6
  • IL6
  • LOC517016
  • il-6
Proteineigenschaft
AA 29-212
20
14
12
6
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Spezies
Rhesusaffen
85
45
30
5
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Quelle
Escherichia coli (E. coli)
136
26
14
7
3
2
2
1
1
Protein-Typ
Recombinant
Biologische Aktivität
Active
Applikation
Functional Studies (Func), SDS-PAGE (SDS)
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Produktmerkmale The recombinant rhesus IL6 consists of 185 amino acids and has a calculated molecular mass of 21 kDa.

Protein Structure: A DNA sequence encoding the the rhesus IL6 (NP_001036198.2 ) (Pro29-Met212) was expressed and purified.
Predicted N-Term: Met
Reinheit > 85 % as determined by SDS-PAGE
Biological Activity Comment Measured in a cell proliferation assay using TF-1 human erythroleukemic cells.
The ED50 for this effect is typically 0.3-1.5 ng/mL.
Molekulargewicht 21 kDa
NCBI Accession NP_001036198
Forschungsgebiet Cancer, Cytokines, Angiogenesis, Innate Immunity
Pathways Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Buffer Lyophilized from sterile 50 % acetonitrile, 0.1 % TFA
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handhabung Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Lagerung -20 °C,-80 °C
Informationen zur Lagerung Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Interleukin 6 (IL6) (AA 29-212) (Active) protein (ABIN2009972) Interleukin 6 (IL6) (AA 29-212) (Active) protein
Allgemeine Veröffentlichungen Chung, Seo, Hur, Kim, Kim, Jung, Kim, Park, Shin: "Association of interleukin-6 promoter variant with bone mineral density in pre-menopausal women." in: Journal of human genetics, Vol. 48, Issue 5, pp. 243-8, 2003 (PubMed).

Heinrich, Behrmann, Müller-Newen, Schaper, Graeve: "Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway." in: The Biochemical journal, Vol. 334 ( Pt 2), pp. 297-314, 1998 (PubMed).

Kishimoto, Akira, Narazaki, Taga: "Interleukin-6 family of cytokines and gp130." in: Blood, Vol. 86, Issue 4, pp. 1243-54, 1995 (PubMed).

Haben Sie etwas anderes gesucht?