Mitogen-Activated Protein Kinase 8 (MAPK8) (full length), (AA 1-427) protein (GST tag)

Details zu Produkt Nr. ABIN2003397, Anbieter: Anmelden zum Anzeigen
Proteinname
  • BSK
  • BSK/DJNK
  • Bsk
  • CG5680
  • D-JNK
  • D-junk
  • DBSK/JNK
  • DJNK
  • DJNK/bsk
  • Dmel\\CG5680
  • JNK
  • JNK/SAPK
  • Jnk
  • Junk
  • SAPKa
  • c-Jun
  • dJNK
  • jnk
  • JNK-46
  • JNK1
  • JNK1A2
  • JNK21B1/2
  • PRKM8
  • SAPK1
  • SAPK1c
  • AI849689
  • Prkm8
  • jnk1
  • sapk1
  • T10F20.15
  • mapk8
  • zgc:112379
  • basket
  • mitogen-activated protein kinase 8
  • mitogen-activated protein kinase 8b
  • Protein JNK-1
  • bsk
  • MAPK8
  • Mapk8
  • mapk8
  • ATMPK8
  • mapk8b
  • jnk-1
Proteineigenschaft
full length, AA 1-427
8
5
3
2
1
1
1
1
1
1
1
1
1
Spezies
Human
17
7
3
1
1
1
Quelle
Baculovirus infected Insect Cells
11
5
4
4
3
2
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
Dieses JNK Protein ist gelabelt mit GST tag.
Applikation
SDS-PAGE (SDS)
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Produktmerkmale The recombinant human MAPK8/GST chimera consists of 652 amino acids and predicts a molecular mass of 75 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the full length of human MAPK8 isoform JNK1 alpha 2 (NP_620637.1) (Met 1-Arg 427) was expressed with the GST tag at the N-terminus.
Predicted N-Term: Met
Reinheit > 90 % as determined by SDS-PAGE
Endotoxin-Niveau < 1.0 EU per μg of the protein as determined by the LAL method
ProductDetails: Biological Activity Comment No Kinase Activity
Hintergrund Synonyms: JNK,JNK-46,JNK1,JNK1A2,JNK21B1/2,PRKM8,SAPK1,SAPK1c
Molekulargewicht 75 kDa, 65 kDa
NCBI Accession NP_620637
Pathways MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Buffer Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 25 % glycerol
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handhabung Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Lagerung -20 °C,-80 °C
Informationen zur Lagerung Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Mitogen-Activated Protein Kinase 8 (MAPK8) (full length), (AA 1-427) protein (GST tag) (ABIN2003397) Mitogen-Activated Protein Kinase 8 (MAPK8) (full length), (AA 1-427) protein (GST tag)
Allgemeine Veröffentlichungen Wiltshire, Matsushita, Tsukada, Gillespie, May: "A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria." in: The Biochemical journal, Vol. 367, Issue Pt 3, pp. 577-85, 2002

Wiltshire, Matsushita, Tsukada, Gillespie, May: "A new c-Jun N-terminal kinase (JNK)-interacting protein, Sab (SH3BP5), associates with mitochondria." in: The Biochemical journal, Vol. 367, Issue Pt 3, pp. 577-85, 2002 (PubMed).

Yazgan, Pfarr: "Regulation of two JunD isoforms by Jun N-terminal kinases." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29710-8, 2002 (PubMed).

Slack, Seternes, Gabrielsen, Keyse: "Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1." in: The Journal of biological chemistry, Vol. 276, Issue 19, pp. 16491-500, 2001 (PubMed).

Haben Sie etwas anderes gesucht?