Casein Kinase 1, alpha 1 (CSNK1A1) (full length), (AA 1-337) (Active) protein (GST tag)

Details zu Produkt Nr. ABIN2003196, Anbieter: Anmelden zum Anzeigen
Proteinname
  • CK1
  • CK1a
  • CKIa
  • HLCDGP1
  • PRO2975
  • 2610208K14Rik
  • 4632404G05Rik
  • 5430427P18Rik
  • Csnk1a
  • CHUNP6894
  • ck1alpha
  • wu:fb65a02
  • wu:fi30h04
  • wu:fj19c11
  • zgc:92158
  • ck1
  • CKIALPHA
  • CG2028
  • CK I
  • CK1alpha
  • CKI
  • CKI alpha
  • CKIalpha
  • CkIa
  • Dmel\\CG2028
  • PKA-C
  • anon-WO03040301.93
  • anon-WO03040301.95
  • ck1a
  • dmCK1
  • dmckI
  • l(1)G0492
  • casein kinase 1 alpha 1
  • casein kinase 1, alpha 1
  • casein kinase 1 alpha 1 L homeolog
  • Casein kinase Ialpha
  • CSNK1A1
  • Csnk1a1
  • csnk1a1
  • csnk1a1.L
  • CkIalpha
Proteineigenschaft
full length, AA 1-337
4
4
4
2
1
1
1
1
1
1
Spezies
Human
10
3
1
1
1
1
1
1
1
Quelle
Baculovirus infected Insect Cells
7
7
3
2
1
Protein-Typ
Recombinant
Biologische Aktivität
Active
Aufreinigungstag / Konjugat
Dieses CSNK1A1 Protein ist gelabelt mit GST tag.
Applikation
Functional Studies (Func), SDS-PAGE (SDS)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktmerkmale The recombinant human CSNK1A1/GST chimera consists of 561 amino acids and predicts a molecular mass of 65.2 kDa. It migrates as an approximately 62 kDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the full length of human CSNK1A1 isoform 1 (P48729-1) (Met 1-Phe 337) was expressed with the GST tag at the N-terminus.
Predicted N-Term: Met
Reinheit > 90 % as determined by SDS-PAGE
Endotoxin-Niveau < 1.0 EU per μg of the protein as determined by the LAL method
ProductDetails: Biological Activity Comment The specific activity was determined to be 30 nmol/min/mg using casein as substrate.
Hintergrund Synonyms: CK1,CK1a,CKIa,HEL-S-77p,HLCDGP1,PRO2975
Molekulargewicht 65.2 kDa, 62 kDa
Pathways WNT Signalweg, Hedgehog Signalweg
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Supplied as sterile 20 mM Tris, 500 mM NaCl, 2 mM GSH, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handhabung Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Lagerung -20 °C,-80 °C
Informationen zur Lagerung Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Haltbarkeit 12 months
Bilder des Herstellers
 image for Casein Kinase 1, alpha 1 (CSNK1A1) (full length), (AA 1-337) (Active) protein (GST tag) (ABIN2003196) Casein Kinase 1, alpha 1 (CSNK1A1) (full length), (AA 1-337) (Active) protein (GST tag)
Allgemeine Veröffentlichungen Wang, Liu, Liu, Ma, Xue, Chen, Zhou: "Gene expression levels of CSNK1A1 and AAC-11, but not NME1, in tumor tissues as prognostic factors in NSCLC patients." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 16, Issue 8, pp. CR357-64, 2010

Wang, Liu, Liu, Ma, Xue, Chen, Zhou: "Gene expression levels of CSNK1A1 and AAC-11, but not NME1, in tumor tissues as prognostic factors in NSCLC patients." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 16, Issue 8, pp. CR357-64, 2010 (PubMed).

Dubois, Kerai, Zemlickova, Howell, Jackson, Venkateswarlu, Cullen, Theibert, Larose, Roach, Aitken: "Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins." in: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 18757-64, 2001 (PubMed).

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