Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) Protein

Details zu Produkt Nr. ABIN2001989, Anbieter: Anmelden zum Anzeigen
Proteinname
  • I-309
  • P500
  • SCYA1
  • SISe
  • TCA3
  • BF534335
  • Scya1
  • Tca-3
  • CCLi6
  • chemokine
  • chemokine (C-C motif) ligand 1
  • CCL1
  • Ccl1
Proteineigenschaft
AA 24-96
9
3
1
1
1
1
Spezies
Human
29
4
Quelle
Escherichia coli (E. coli)
18
2
2
2
1
1
Protein-Typ
Recombinant
Applikation
SDS-PAGE (SDS)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Produktmerkmale The recombinant human CCL1 consists of 75 amino acids and predicts a molecular mass of 8.7 KDa. It migrates as an approximately 9 KDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the human CCL1 (P22362) (Lys24-Lys96) was expressed, with a N-terminal Met.
Predicted N-Term: Met
Reinheit > 95 % as determined by SDS-PAGE
Hintergrund Synonyms: I-309,P500,SCYA1,SISe,TCA3
UniProt P22362
Applikationshinweise Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Buffer Lyophilized from sterile 40 % acetonitrile, 0.1 % TFA, 20 % H2O
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handhabung Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Lagerung -20 °C,-80 °C
Informationen zur Lagerung Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Haltbarkeit 12 months
Bilder des Herstellers
SDS-PAGE (SDS) image for Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) protein (ABIN2001989) Chemokine (C-C Motif) Ligand 1 (CCL1) (AA 24-96) protein
Allgemeine Veröffentlichungen Spinetti, Bernardini, Camarda, Mangoni, Santoni, Capogrossi, Napolitano: "The chemokine receptor CCR8 mediates rescue from dexamethasone-induced apoptosis via an ERK-dependent pathway." in: Journal of leukocyte biology, Vol. 73, Issue 1, pp. 201-7, 2003 (PubMed).

Bernardini, Spinetti, Ribatti, Camarda, Morbidelli, Ziche, Santoni, Capogrossi, Napolitano: "I-309 binds to and activates endothelial cell functions and acts as an angiogenic molecule in vivo." in: Blood, Vol. 96, Issue 13, pp. 4039-45, 2000 (PubMed).

Horuk, Hesselgesser, Zhou, Faulds, Halks-Miller, Harvey, Taub, Samson, Parmentier, Rucker, Doranz, Doms: "The CC chemokine I-309 inhibits CCR8-dependent infection by diverse HIV-1 strains." in: The Journal of biological chemistry, Vol. 273, Issue 1, pp. 386-91, 1998 (PubMed).

Roos, Loetscher, Legler, Clark-Lewis, Baggiolini, Moser: "Identification of CCR8, the receptor for the human CC chemokine I-309." in: The Journal of biological chemistry, Vol. 272, Issue 28, pp. 17251-4, 1997 (PubMed).

Miller, Krangel: "The human cytokine I-309 is a monocyte chemoattractant." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 7, pp. 2950-4, 1992 (PubMed).

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