OBFC1 Protein (AA 1-368) (His tag)

Produktnummer ABIN1692233

Produktdetails

Target: OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-368

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses OBFC1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human OBFC1/CST Complex Subunit STN1 (N-6His)

Sequenz: MGSSHHHHHH SSGLVPRGSH MQPGSSRCEE ETPSLLWGLD PVFLAFAKLY IRDILDMKES RQVPGVFLYN GHPIKQVDVL GTVIGVRERD AFYSYGVDDS TGVINCICWK KLNTESVSAA PSAARELSLT SQLKKLQETI EQKTKIEIGD TIRVRGSIRT YREEREIHAT AYYKVDDPVW NIQIARMLEL PTIYRKVYDQ PFHSSALEKE EALSNPGALD LPSLTSLLSE KAKEFLMENR VQSFYQQELE MVESLLSLAN QPVIHSACSD QVNFKKDTTS KAIHSIFKNA IQLLQEKGLV FQKDDGFDNL YYVTREDKDL HRKIHRIIQQ DCQKPNHMEK GCHFLHILAC ARLSIRPGLS EAVLQQVLEL LEDQSDIVST MEHYYTAF

Produktmerkmale: Recombinant Human Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1/OBFC1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Phe368) of Human OBFC1 fused with a His tag at the N-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 1 mM DTT, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))

Andere Bezeichnung: Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1/OBFC1 (OBFC1 Produkte)

Synonyme: AAF-44 Protein, AAF44 Protein, RP11-541N10.2 Protein, RPA-32 Protein, STN1 Protein, bA541N10.2 Protein, 0610009H20Rik Protein, 2310057J23Rik Protein, AI413458 Protein, zgc:64174 Protein, ATSTN1 Protein, F10K1.17 Protein, F10K1_17 Protein, STN1, CST complex subunit Protein, Nucleic acid-binding, OB-fold-like protein Protein, STN1 Protein, Stn1 Protein, stn1 Protein

Sub Type: Fusionprotein

Hintergrund: CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Alternative Names: CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1

Molekulargewicht: 44.2 kDa

UniProt: Q9H668