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RANKL Protein (AA 157-316, Soluble) (Fc Tag)

TNFSF11 Spezies: Maus Wirt: HEK-293 Cells Recombinant >95 % (SDS-PAGE) SDS Active
Produktnummer ABIN1344301
  • Target Alle RANKL (TNFSF11) Proteine anzeigen
    RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Soluble, AA 157-316
    Spezies
    • 35
    • 22
    • 4
    • 2
    Maus
    Quelle
    • 25
    • 20
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses RANKL Protein ist gelabelt mit Fc Tag.
    Applikation
    SDS-PAGE (SDS)
    Spezifität
    Binds to mouse RANK.
    Kreuzreaktivität
    Maus
    Produktmerkmale
    Mouse RANKL (aa 157-316) is fused at the N-terminus to the Fc portion of human IgG1.
    Reinheit
    >95 % (SDS-PAGE)
    Endotoxin-Niveau
    <0.01EU/μg purified protein (LAL test, Lonza).
    Top Product
    Discover our top product TNFSF11 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Induces osteoclastogenesis of bone marrow-derived macrophages.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with 100 μL sterile water.
    Konzentration
    Lot specific
    Buffer
    Lyophilized. Contains PBS.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Beleut, Rajaram, Caikovski, Ayyanan, Germano, Choi, Schneider, Brisken: "Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 7, pp. 2989-94, (2010) (PubMed).

  • Target
    RANKL (TNFSF11) (Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11))
    Andere Bezeichnung
    Fc :RANKL (TNFSF11 Produkte)
    Synonyme
    CD254 Protein, ODF Protein, OPGL Protein, OPTB2 Protein, RANKL Protein, TRANCE Protein, hRANKL2 Protein, sOdf Protein, TNFSF11 Protein, Ly109l Protein, OPG Protein, Trance Protein, cd254 Protein, odf Protein, opgl Protein, optb2 Protein, rankl Protein, sodf Protein, tnfsf11 Protein, trance Protein, TNF superfamily member 11 Protein, tumor necrosis factor (ligand) superfamily, member 11 Protein, TNF receptor superfamily member 11b Protein, TNF superfamily member 11 L homeolog Protein, TNFSF11 Protein, Tnfsf11 Protein, TNFRSF11B Protein, tnfsf11.L Protein
    Hintergrund
    RANKL is an osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T cell proliferation. Important regulator of interactions between T cells and dendritic cells and may play a role in the regulation of the T cell-dependent immune response. RANKL plays an important role in the progression of Breast cancer.
    Molekulargewicht
    ~55kDa (SDS-PAGE)
    UniProt
    O35235
    Pathways
    NF-kappaB Signalweg
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