Nicotinamide phosphoribosyltransferase (NAMPT) (AA 1-491) (Active) protein (His tag)

Details zu Produkt Nr. ABIN1344090, Anbieter: Anmelden zum Anzeigen
Proteinname
  • PBEF1
  • pbef
  • pbef1
  • 1110035O14Rik
  • PBEF
  • VF
  • VISFATIN
  • AI314458
  • AI480535
  • NAmPRTase
  • Pbef
  • Pbef1
  • Visfatin
  • visfatin
  • nicotinamide phosphoribosyltransferase
  • Nicotinamide phosphoribosyltransferase
  • NAMPT
  • nampt
  • Smon_0680
  • Mrub_2845
  • Cseg_3704
  • BC1002_3997
  • Ftrac_2686
  • Varpa_5681
  • Celal_3900
  • Deima_0880
  • BC1001_3724
  • Celly_1696
  • Clole_1542
  • Psed_2146
  • Psed_2158
  • Tsp_05934
  • Nampt
Proteineigenschaft
AA 1-491
18
5
2
2
1
Spezies
Maus
34
13
8
1
1
Quelle
Escherichia coli (E. coli)
34
4
2
2
2
1
1
Protein-Typ
Recombinant
Biologische Aktivität
Active
Aufreinigungstag / Konjugat
Dieses NAMPT Protein ist gelabelt mit His tag.
Applikation
SDS-PAGE (SDS)
Optionen
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Kreuzreaktivität Maus
Produktmerkmale Mouse Nampt (visfatin/PBEF) (aa 1-491) is fused at the C-terminus to a His-tag.
Reinheit >90 % (SDS-PAGE)
Sterilität 0.2 μm filtered
Endotoxin-Niveau <1EU/μg purified protein (LAL test, Lonza).
Hintergrund Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Molekulargewicht ~52kDa (SDS-PAGE)
UniProt Q99KQ4
Applikationshinweise Optimal working dilution should be determined by the investigator.
Kommentare

Shows adipogenic effects in stimulated differentiating 3T3-L1 cells.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute in distilled water.
Buffer Lyophilized from 0.2μm-filtered solution in PBS, pH 7.2.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.
Haltbarkeit 3 months
Produkt verwendet in: Brown, Onyango, Ramanjaneya, Conner, Patel, Dunmore, Randeva: "Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes-related genes in mouse pancreatic beta-cells." in: Journal of molecular endocrinology, Vol. 44, Issue 3, pp. 171-8, 2010 (PubMed).