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CCL2 Protein

CCL2 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant ≥ 95 % ELISA, Func
Produktnummer ABIN1305101
  • Target Alle CCL2 Proteine anzeigen
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Protein-Typ
    Recombinant
    Spezies
    • 23
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 34
    • 12
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    ELISA, Functional Studies (Func)
    Marke
    BD Pharmingen™
    Spezifität
    Bioactivity: This material has been reported to have bioactivity when measured by Ca 2+ Flux Assay, using Human THP-1cells. The EC50 is commonly in the range of 20-350 ng/ml. Unit is defined as the amount of material required to stimulate a half-maximal response at cytokine saturation. Carrier proteins should be pre-screened for possible effects in an appropriate experimental system. Carrier proteins may effect experimental results due to toxicity, high endotoxin levels or possible blocking activity.
    Produktmerkmale
    Recombinant human MCP-1 is supplied as a frozen liquid comprised of 0.22 µm sterile-filtered aqueous buffered solution (pH 7.2) and containing 2 mg/ml biotechnology grade, low endotoxin bovine serum albumin, with no preservatives. The human MCP-1 is ≥ 95% pure as determined by SDS-PAGE, and an absorbance assay based on the Beers-Lambert law.
    Aufreinigung
    Recombinant human MCP-1 is supplied as a frozen liquid comprised of 0.22 μm sterile-filtered aqueous buffered solution and bovine serum albumin, with no preservatives. Recombinant human MCP-1 is ≥ 95 % pure as determined by SDS-PAGE, and an absorbance assay based on the Beers-Lambert law.
    Reinheit
    ≥ 95 %
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    The endotoxin level is ≤ 0.1 ng per µg of human MCP-1, as measured in a chromogenic LAL assay.
    Top Product
    Discover our top product CCL2 Protein
  • Applikationshinweise
    ELISA Standard: The human MCP-1 (Cat. No. 554620) is useful as a quantitative standard for measuring human MCP-1 protein levels in a sandwich ELISA with the purified 10F7 antibody (Cat. No. 555055) as a capture antibody and the biotinylated 5D3-F7 (Cat. No. 554664) as the detection antibody. To obtain linear standard curves, doubling dilutions of this human MCP-1 standard from 2000-4 pg/ml should be included in each ELISA plate.
    Kommentare

    BD Pharmingen™ Recombinant Human MCP-1

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    200 μg/mL
    Buffer
    Frozen aqueous buffered solution containing BSA.
    Konservierungsmittel
    Azide free
    Handhabung
    Human monocyte chemoattractant protein-1 (MCP-1), also known as MCAF (monocyte chemotactic and activating factor), is a member of CC chemokine family. MCP-1 is produced by a variety of stimulated cell types including monocytes, lymphocytes, endothelial cells and fibroblasts. MCP-1 is a potent chemoattractant for monocytes and it also activates lymphocytes, basophils and NK cells.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store product at -80°C prior to use or for long term storage of stock solutions. Rapidly thaw and quick-spin product prior to use. Avoid multiple freeze-thaws of product. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Rollins: "Chemokines." in: Blood, Vol. 90, Issue 3, pp. 909-28, (1997) (PubMed).

    Rollins, Stier, Ernst, Wong: "The human homolog of the JE gene encodes a monocyte secretory protein." in: Molecular and cellular biology, Vol. 9, Issue 11, pp. 4687-95, (1990) (PubMed).

  • Target
    CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
    Andere Bezeichnung
    MCP-1 (CCL2 Produkte)
    Synonyme
    GDCF-2 Protein, HC11 Protein, HSMCR30 Protein, MCAF Protein, MCP-1 Protein, MCP1 Protein, SCYA2 Protein, SMC-CF Protein, AI323594 Protein, JE Protein, Scya2 Protein, Sigje Protein, MCP-1A Protein, MCP1A Protein, C-C motif chemokine ligand 2 Protein, chemokine (C-C motif) ligand 2 Protein, C-C motif chemokine 2 Protein, CCL2 Protein, Ccl2 Protein, LOC101120093 Protein
    Hintergrund
    Human monocyte chemoattractant protein-1 (MCP-1), also known as MCAF (monocyte chemotactic and activating factor), is a member of CC chemokine family. MCP-1 is produced by a variety of stimulated cell types including monocytes, lymphocytes, endothelial cells and fibroblasts. MCP-1 is a potent chemoattractant for monocytes and it also activates lymphocytes, basophils and NK cells.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylierungen bei SARS-CoV-2 Infektion
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