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PQBP1 Protein (His tag)

PQBP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Produktnummer ABIN1098284
  • Target Alle PQBP1 Proteine anzeigen
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    Protein-Typ
    Recombinant
    Spezies
    • 11
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses PQBP1 Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Aufreinigung
    purified by chromatography
    Reinheit
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product PQBP1 Protein
  • Kommentare

    Synonyms: Polyglutamine binding protein 1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 20% glycerol, 1 MM DTT
    Lagerung
    4 °C
    Informationen zur Lagerung
    Avoid repeated freezing and thawing cycles.
  • Target
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    Andere Bezeichnung
    PQBP1 (PQBP1 Produkte)
    Synonyme
    PQBP1 Protein, MRX55 Protein, MRXS3 Protein, MRXS8 Protein, NPW38 Protein, RENS1 Protein, SHS Protein, PQBP-1 Protein, Sfc2 Protein, npw38 Protein, polyglutamine binding protein 1 Protein, PQBP1 Protein, Pqbp1 Protein
    Hintergrund
    Polyglutamine binding protein 1, also known as PQBP1, is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. Recombinant human PQBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
    Molekulargewicht
    33 kDa (289aa), confirmed by MALDI-TOF
    NCBI Accession
    NP_005701
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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