CHMP6 Protein (His tag)

Produktnummer ABIN1098261

Produktdetails

Target: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses CHMP6 Protein ist gelabelt mit His tag.

Applikation: SDS-PAGE (SDS)

Aufreinigung: purified by chromatography

Reinheit: > 95 % by SDS - PAGE

Anwendungsinformationen

Kommentare:

Synonyms: charged multivesicular body protein 6, VPS20

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl

Lagerung: 4 °C

Informationen zur Lagerung: Avoid repeated freezing and thawing cycles.

Antigendetails

Target: CHMP6 (Charged Multivesicular Body Protein 6 (CHMP6))

Andere Bezeichnung: CHMP6 (CHMP6 Produkte)

Synonyme: chmp6 Protein, vps20 Protein, 2400004G01Rik Protein, VPS20 Protein, RGD1565325 Protein, chmp6l Protein, flj11749l Protein, wu:fb79d02 Protein, zgc:110067 Protein, charged multivesicular body protein 6 Protein, charged multivesicular body protein 6 L homeolog Protein, charged multivesicular body protein 6 S homeolog Protein, charged multivesicular body protein 6b Protein, LOC100280982 Protein, chmp6.L Protein, chmp6.S Protein, CHMP6 Protein, chmp6 Protein, Tsp_08316 Protein, Chmp6 Protein, chmp6b Protein

Hintergrund: CHMP6, as known as charged multivesicular body protein 6, belongs to the SNF7 family. This Protein is core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Recombinant human CHMP6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molekulargewicht: 26.1kDa (225aa), confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)

NCBI Accession: NP_078867