RANBP1 Protein (His tag)
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- Target Alle RANBP1 Proteine anzeigen
- RANBP1 (RAN Binding Protein 1 (RANBP1))
- Protein-Typ
- Recombinant
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses RANBP1 Protein ist gelabelt mit His tag.
- Applikation
- SDS-PAGE (SDS)
- Aufreinigung
- purified by chromatography
- Reinheit
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product RANBP1 Protein
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- Kommentare
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Synonyms: RAN binding protein 1, HTF9A
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 1 MM DTT, 10% glycerol, 0.1 M NaCl
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Avoid repeated freezing and thawing cycles.
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- Target
- RANBP1 (RAN Binding Protein 1 (RANBP1))
- Andere Bezeichnung
- RANBP1 (RANBP1 Produkte)
- Hintergrund
- RAN binding protein 1, also known as RANBP1, belongs to a family of proteins that bind Ran GTPase which is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). Also, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. Recombinant human RANBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molekulargewicht
- 25.8 kDa (225aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- NCBI Accession
- NP_002873
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