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TARDBP Protein (His tag)

TARDBP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Produktnummer ABIN1098222
  • Target Alle TARDBP Proteine anzeigen
    TARDBP (TAR DNA Binding Protein (TARDBP))
    Protein-Typ
    Recombinant
    Spezies
    • 11
    • 3
    • 1
    • 1
    Human
    Quelle
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses TARDBP Protein ist gelabelt mit His tag.
    Applikation
    SDS-PAGE (SDS)
    Aufreinigung
    purified by chromatography
    Reinheit
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product TARDBP Protein
  • Kommentare

    Synonyms: TAR DNA binding protein, ALS10, TDP43

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1 M NaCl
    Lagerung
    4 °C
    Informationen zur Lagerung
    Avoid repeated freezing and thawing cycles.
  • Target
    TARDBP (TAR DNA Binding Protein (TARDBP))
    Andere Bezeichnung
    TARDBP (TARDBP Produkte)
    Synonyme
    TARDBP Protein, TDP43 Protein, DKFZp459I2127 Protein, tardbp Protein, ALS10 Protein, TDP-43 Protein, 1190002A23Rik Protein, C85084 Protein, Tdp43 Protein, wu:fb77f02 Protein, wu:fc52g10 Protein, TAR DNA binding protein Protein, Tardbp protein Protein, TAR DNA binding protein L homeolog Protein, TAR DNA-binding protein 43-like Protein, TARDBP Protein, tardbp Protein, tardbp.L Protein, Tardbp Protein, LOC100621383 Protein
    Hintergrund
    TARDBP was originally identified as a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. It has also been identified in individuals diagnosed with chronic traumatic encephalopathy, a condition that often mimics ALS and that has been associated with athletes who have experienced multiple concussions and other types of head injury. It has been shown to bind both DNA and RNA and have multiple functions in transcriptional repression, pre-mRNA splicing and translational regulation. Recombinant human TARDBP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
    Molekulargewicht
    33.6 kDa(296aa) confirmed by MALDI-TOF
    NCBI Accession
    NP_031401
    Pathways
    Positive Regulation of Peptide Hormone Secretion
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