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POMGNT1 Protein (AA 1-660) (His tag)

POMGNT1 Spezies: Human Wirt: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Produktnummer ABIN1097427
  • Target Alle POMGNT1 Proteine anzeigen
    POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 1-660
    Spezies
    • 6
    • 2
    Human
    Quelle
    • 4
    • 2
    • 1
    • 1
    Human Cells
    Aufreinigungstag / Konjugat
    Dieses POMGNT1 Protein ist gelabelt mit His tag.
    Verwendungszweck
    Recombinant Human POMGNT1 (C-6His)
    Sequenz
    LDTRRAISEA NEDPEPEQDY DEALGRLEPP RRRGSGPRRV LDVEVYSSRS KVYVAVDGTT VLEDEAREQG RGIHVIVLNQ ATGHVMAKRV FDTYSPHEDE AMVLFLNMVA PGRVLICTVK DEGSFHLKDT AKALLRSLGS QAGPALGWRD TWAFVGRKGG PVFGEKHSKS PALSSWGDPV LLKTDVPLSS AVEAECHWAD TELNRRRRRF CSKVEGYGSV CSCKDPTPIE FSPDPLPDNK VLNVPVAVIA GNRPNYLYRM LRSLLSAQGV SPQMITVFID GYYEEPMDVV ALFGLRGIQH TPISIKNARV SQHYKASLTA TFNLFPEAKF AVVLEEDLDI AVDFFSFLSQ SIHLLEEDDS LYCISAWNDQ GYEHTAEDPA LLYRVETMPG LGWVLRRSLY KEELEPKWPT PEKLWDWDMW MRMPEQRRGR ECIIPDVSRS YHFGIVGLNM NGYFHEAYFK KHKFNTVPGV QLRNVDSLKK EAYEVEVHRL LSEAEVLDHS KNPCEDSFLP DTEGHTYVAF IRMEKDDDFT TWTQLAKCLH IWDLDVRGNH RGLWRLFRKK NHFLVVGVPA SPYSVKKPPS VTPIFLEPPP KEEGAPGAPE QTVDHHHHHH
    Produktmerkmale
    Recombinant Human Protein O-Linked-Mannose beta-1 2-N-Acetylglucosaminyltransferase 1/POMGNT1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Thr660) of Human POMGNT1 fused with a polyhistidine tag at the C-terminus.
    Reinheit
    > 95 % as determined by reducing SDS-PAGE.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product POMGNT1 Protein
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 10 % Glycerol, pH 8.5.
    Handhabung
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    POMGNT1 (Protein O-Linked Mannose Beta1,2-N-Acetylglucosaminyltransferase (POMGNT1))
    Andere Bezeichnung
    POMGNT1 (POMGNT1 Produkte)
    Synonyme
    POMGNT1 Protein, im:7151461 Protein, zgc:158130 Protein, 0610016I07Rik Protein, 4930467B06Rik Protein, GNTI.2 Protein, GnT I.2 Protein, LGMD2O Protein, MDDGA3 Protein, MDDGB3 Protein, MDDGC3 Protein, MEB Protein, MGAT1.2 Protein, gnT-I.2 Protein, protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Protein, protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) S homeolog Protein, protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase Protein, POMGNT1 Protein, pomgnt1.S Protein, pomgnt1 Protein, Pomgnt1 Protein
    Sub Type
    Fusionprotein
    Hintergrund
    Protein O-Linked-Mannose beta-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
    Alternative Names: Protein O-Linked-Mannose Beta-1,2-N-Acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1,2-N-Acetylglucosaminyltransferase I.2, GnT I.2, POMGNT1, MGAT1.2
    Molekulargewicht
    69.3 kDa
    UniProt
    Q8WZA1
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