PYM Protein (AA 1-204) (His tag)

Produktnummer ABIN1097293

Produktdetails

Target: PYM (WIBG) (Partner of Y14 and mago (WIBG))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-204

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PYM Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human Partner of Y14 and Mago/WIBG /PYM (C-6His)

Sequenz: MEAAGSPAAT ETGKYIASTQ RPDGTWRKQR RVKEGYVPQE EVPVYENKYV KFFKSKPELP PGLSPEATAP VTPSRPEGGE PGLSKTAKRN LKRKEKRRQQ QEKGEAEALS RTLDKVSLEE TAQLPSAPQG SRAAPTAASD QPDSAATTEK AKKIKNLKKK LRQVEELQQR IQAGEVSQPS KEQLEKLARR RALEEELEDL ELGLLEHHHH HH

Produktmerkmale: Recombinant Human Partner of Y14 and Mago/WIBG is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu204) of Human WIBG fused with a 6His tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 100 mM NaCl, 10 % Glycerol, pH 8.0.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: -80 °C

Informationen zur Lagerung: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Haltbarkeit: 6 months

Antigendetails

Target: PYM (WIBG) (Partner of Y14 and mago (WIBG))

Andere Bezeichnung: WIBG (WIBG Produkte)

Synonyme: BEST:HL05757 Protein, CG10330 Protein, CG30176 Protein, Dmel\\CG30176 Protein, PYM Protein, Pym Protein, UD3 Protein, A030010B05Rik Protein, zgc:65891 Protein, zgc:77281 Protein, Partner of Y14 and Mago Protein, Wibg protein Protein, PYM homolog 1, exon junction complex associated factor L homeolog Protein, PYM homolog 1, exon junction complex associated factor Protein, Pym Protein, wibg Protein, pym1.L Protein, PYM1 Protein, Pym1 Protein, pym1 Protein

Sub Type: Fusionprotein

Hintergrund: Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for the intron exon structure of genes, and directs post-transcriptional processes in the cytoplasm, for instance mRNA export, nonsense-mediated mRNA decay or translation. WIBG is a cytoplasmic RNA-binding protein, it can be excluded from nucleus by Crm1. WIBG as a cooperateing partner of Mago-14, relates with Mago-14 by its N-terminal domain.
Alternative Names: Partner of Y14 and Mago, Protein Wibg Homolog, WIBG, PYM

Molekulargewicht: 23.7 kDa

UniProt: Q9BRP8