SPINT2 Protein (AA 28-197) (His tag)

Produktnummer ABIN1096804

Produktdetails

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Protein-Typ: Recombinant

Proteineigenschaft: AA 28-197

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses SPINT2 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human HAI-2/KOP/SPINT2 (C-6His)

Sequenz: ADRERSIHDF CLVSKVVGRC RASMPRWWYN VTDGSCQLFV YGGCDGNSNN YLTKEECLKK CATVTENATG DLATSRNAAD SSVPSAPRRQ DSEDHSSDMF NYEEYCTANA VTGPCRASFP RWYFDVERNS CNNFIYGGCR GNKNSYRSEE ACMLRCFRQQ ENPPLPLGSK VDHHHHHH

Produktmerkmale: Recombinant Human Hepatocyte Growth Factor Activator Inhibitor Type 2/HAI2 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Ala28-Lys197) of Human HAI2 fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))

Andere Bezeichnung: hai-2 (SPINT2 Produkte)

Synonyme: HAI-2 Protein, Pb Protein, DIAR3 Protein, HAI2 Protein, Kop Protein, PB Protein, AL024025 Protein, C76321 Protein, serine peptidase inhibitor, Kunitz type, 2 Protein, serine peptidase inhibitor, Kunitz type 2 Protein, serine protease inhibitor, Kunitz type 2 Protein, Spint2 Protein, SPINT2 Protein

Sub Type: Fusionprotein

Hintergrund: Hepatocyte Growth Factor Activator Inhibitor Type 2 (HAI2) is a single-pass type I membrane protein and contains two BPTI/Kunitz inhibitor domains. The first Kunitz domain is mainly responsible for the inhibitory activity against hepatocyte growth factor activator (HGFA). HAI2 is expressed in placenta, kidney, pancreas, prostate, testis, thymus and trachea. HAI2 serves as a inhibitor of HGF activator. It also inhibits plasmin, plasma and tissue kallikrein and factor XIa. Defects in HAI2 are the cause of diarrhea type 3 (DIAR3), also known as congenital sodium diarrhea (CSD).
Alternative Names: Kunitz-Type Protease Inhibitor 2, Hepatocyte Growth Factor Activator Inhibitor Type 2, HAI-2, Placental Bikunin, SPINT2, HAI2, KOP

Molekulargewicht: 20.22 kDa

UniProt: O43291