CLEC4E Protein (AA 41-219) (His tag)

Produktnummer ABIN1096407

Produktdetails

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Protein-Typ: Recombinant

Proteineigenschaft: AA 41-219

Spezies: Human

Quelle: Human Cells

Aufreinigungstag / Konjugat: Dieses CLEC4E Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human CLEC4E/Mincel (C-6His)

Sequenz: RCVVTFRIFQ TCDEKKFQLP ENFTELSCYN YGSGSVKNCC PLNWEYFQSS CYFFSTDTIS WALSLKNCSA MGAHLVVINS QEEQEFLSYK KPKMREFFIG LSDQVVEGQW QWVDGTPLTK SLSFWDVGEP NNIATLEDCA TMRDSSNPRQ NWNDVTCFLN YFRICEMVGI NPLNKGKSLV DHHHHHH

Produktmerkmale: Recombinant Human C-Type Lectin Domain Family 4 Member E/CLEC4E is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Arg41-Leu219) of Human CLEC4E fused with a polyhistidine tag at the C-terminus.

Reinheit: > 95 % as determined by reducing SDS-PAGE.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handhabung: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Lagerung: 4 °C/-20 °C/-80 °C

Informationen zur Lagerung: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Haltbarkeit: 3 months

Antigendetails

Target: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Andere Bezeichnung: clec4e (CLEC4E Produkte)

Synonyme: CLECSF9 Protein, MINCLE Protein, C86253 Protein, Clecsf9 Protein, Mincle Protein, CLEC4E Protein, C-type lectin domain family 4 member E Protein, C-type lectin domain family 4, member e Protein, C-type lectin domain family 4, member E Protein, CLEC4E Protein, Clec4e Protein, LOC611538 Protein

Sub Type: Fusionprotein

Hintergrund: C-Type Lectin Domain Family 4 Member E (CLEC4E) is a 219 amino acid single-pass type II membrane protein that contains one C-type Lectin domain. It is expressed in monocytes, CLEC4E functions as a downstream target of C/EBP beta and is thought to play a role in the inflammatory response, possibly via transcriptional control of C/EBP beta. CLEC4E may play a role in the response to inflammatory stimuli in peritoneal macrophages and may be involved in immune surveillance processes under transcriptional control of CEBPB. Human CLEC4E shares 67% sequence identity with its mouse counterpart, suggesting a similar function between species. CLEC-4E exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to a natural killer gene complex region on human chromosome 12.
Alternative Names: C-Type Lectin Domain Family 4 Member E, C-Type Lectin Superfamily Member 9, Macrophage-Inducible C-Type Lectin, CLEC4E, CLECSF9, MINCLE

Molekulargewicht: 21.7 kDa

UniProt: Q9ULY5