Interleukin 8 (IL8) (AA 23-99), (full length) protein (His tag)

Details zu Produkt Nr. ABIN1047264, Anbieter: Anmelden zum Anzeigen
Proteinname
  • IL8
  • K60
  • interleukin-8
  • il8
  • si:dkey-151b16.2
  • cxcli2
  • Il8
  • Scyb15
  • lungkine
  • weche
  • CXCL8
  • GCP-1
  • GCP1
  • LECT
  • LUCT
  • LYNAP
  • MDNCF
  • MONAP
  • NAF
  • NAP-1
  • NAP1
  • IL-8
  • AMCF-I
  • EMF-1
  • interleukin 8-like 1
  • interleukin 8
  • C-X-C motif chemokine ligand 8
  • chemokine (C-X-C motif) ligand 8a
  • chemokine (C-X-C motif) ligand 1-like
  • chemokine (C-X-C motif) ligand 15
  • interleukin 8-like 2
  • IL8L1
  • il8
  • CXCL8
  • cxcl8a
  • IL8
  • LOC422654
  • Cxcl15
  • Cxcl8
  • IL8L2
Proteineigenschaft
AA 23-99, full length
17
14
12
7
4
4
4
2
2
1
1
1
1
1
1
1
1
1
1
1
Spezies
Human
100
7
7
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Quelle
Escherichia coli (E. coli)
109
15
4
2
2
2
2
1
1
1
1
Protein-Typ
Recombinant
Aufreinigungstag / Konjugat
Dieses Interleukin 8 Protein ist gelabelt mit His tag.
Applikation
ELISA
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Sequenz AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS
Produktmerkmale Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
Reinheit 90 %
Hintergrund IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Molekulargewicht 13 kD
UniProt P10145
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagie
Kommentare

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Konzentration 0.2-2 mg/mL
Buffer Tris-based buffer, 50 % glycerol
Handhabung Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
Bilder des Herstellers
SDS-PAGE (SDS) image for Interleukin 8 (IL8) (AA 23-99), (full length) protein (His tag) (ABIN1047264) Interleukin 8 (IL8) (AA 23-99), (full length) protein (His tag)
Allgemeine Veröffentlichungen Schröder: "Biochemical and biological characterization of NAP-1/IL-8-related cytokines in lesional psoriatic scale." in: Advances in experimental medicine and biology, Vol. 305, pp. 97-107, 1992 (PubMed).

Van Damme, Rampart, Conings, Decock, Van Osselaer, Willems, Billiau: "The neutrophil-activating proteins interleukin 8 and beta-thromboglobulin: in vitro and in vivo comparison of NH2-terminally processed forms." in: European journal of immunology, Vol. 20, Issue 9, pp. 2113-8, 1990 (PubMed).

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