COMMD4 Protein (AA 1-195, partial) (GST tag)

Produktnummer ABIN1046851

Produktdetails

Target: COMMD4 (COMM Domain Containing 4 (COMMD4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-195, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses COMMD4 Protein ist gelabelt mit GST tag.

Applikation: ELISA

Sequenz: MRFRFCGDLD CPDWVLAEIS TLAKMSSVKL RLLCSQVLKE LLGQGIDYEK ILKLTADAKF ESGDVKATVA VLSFILSSAA KHSVDGESLS SELQQLGLPK EHAASLCRCY EEKQSPLQKH LRVCSLRMNR LAGVGWRVDY TLSSSLLQSV EEPMVHLRLE VAAAPGTPAQ PVAMSLSADK FQVLLAELKQ AQTLM

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Referenzen

Burstein, Hoberg, Wilkinson, Rumble, Csomos, Komarck, Maine, Wilkinson, Mayo, Duckett: "COMMD proteins, a novel family of structural and functional homologs of MURR1." in: The Journal of biological chemistry, Vol. 280, Issue 23, pp. 22222-32, (2005) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Wiemann, Weil, Wellenreuther, Gassenhuber, Glassl, Ansorge, Böcher, Blöcker, Bauersachs, Blum, Lauber, Düsterhöft, Beyer, Köhrer, Strack, Mewes, Ottenwälder, Obermaier, Tampe, Heubner, Wambutt, Korn et al.: "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. ..." in: Genome research, Vol. 11, Issue 3, pp. 422-35, (2001) (PubMed).

Antigendetails

Target: COMMD4 (COMM Domain Containing 4 (COMMD4))

Andere Bezeichnung: COMM domain-containing protein 4 protein (COMMD4 Produkte)

Synonyme: zgc:153556 Protein, 1110039H05Rik Protein, COMM domain containing 4 Protein, COMM domain containing 4 S homeolog Protein, commd4 Protein, commd4.S Protein, COMMD4 Protein, Commd4 Protein

Hintergrund: Down-regulates activation of NF-kappa-B. Ref.1

Molekulargewicht: 48.8 kD

UniProt: Q9H0A8