Cathepsin D Protein (CTSD) (AA 67-403, partial) (GST tag)

Produktnummer ABIN1046776

Produktdetails

Target: Cathepsin D (CTSD)

Protein-Typ: Recombinant

Proteineigenschaft: AA 67-403, partial

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses Cathepsin D Protein ist gelabelt mit GST tag.

Applikation: ELISA

Sequenz: IPEVLKNYMD AQYYGEIGIG TPPQCFTVVF DTGSSNLWVP SIHCKLLDIA CWIHHKYNSD KSSTYVKNGT SFDIHYGSGS LSGYLSQDTV SVPCQSASSA SALGGVKVER QVFGEATKQP GITFIAAKFD GILGMAYPRI SVNNVLPVFD NLMQQKLVDQ NIFSFYLSRD PDAQPGGELM LGGTDSKYYK GSLSYLNVTR KAYWQVHLDQ VEVASGLTLC KEGCEAIVDT GTSLMVGPVD EVRELQKAIG AVPLIQGEYM IPCEKVSTLP AITLKLGGKG YKLSPEDYTL KVSQAGKTLC LSGFMGMDIP PPSGPLWILG DVFIGRYYTV FDRDNNR

Produktmerkmale: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Reinheit: 90 %

Anwendungsinformationen

Kommentare:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handhabung: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Referenzen

Redecker, Heckendorf, Grosch, Mersmann, Hasilik: "Molecular organization of the human cathepsin D gene." in: DNA and cell biology, Vol. 10, Issue 6, pp. 423-31, (1991) (PubMed).

Westley, May: "Oestrogen regulates cathepsin D mRNA levels in oestrogen responsive human breast cancer cells." in: Nucleic acids research, Vol. 15, Issue 9, pp. 3773-86, (1987) (PubMed).

Faust, Kornfeld, Chirgwin: "Cloning and sequence analysis of cDNA for human cathepsin D." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 15, pp. 4910-4, (1985) (PubMed).

Antigendetails

Target: Cathepsin D (CTSD)

Andere Bezeichnung: Cathepsin D protein (CTSD Produkte)

Synonyme: catD Protein, fb93e11 Protein, fj17b09 Protein, wu:fb93e11 Protein, wu:fj17b09 Protein, LOC398557 Protein, Cathd Protein, CatD Protein, LOC100136761 Protein, CTSD Protein, DKFZp469J0315 Protein, DDBDRAFT_0205785 Protein, DDBDRAFT_0215012 Protein, DDB_0205785 Protein, DDB_0215012 Protein, CLN10 Protein, CPSD Protein, CD Protein, cathepsin D Protein, cathepsin D S homeolog Protein, lysosomal aspartic protease Protein, cathepsin D-like Protein, ctsd Protein, LOC398557 Protein, ctsd.S Protein, CatD Protein, LOC5567565 Protein, LOC100136761 Protein, CTSD Protein, Cathd Protein, ctsD Protein, catd Protein, Ctsd Protein, LOC443060 Protein

Hintergrund: Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Molekulargewicht: 64.2 kD

UniProt: P07339

Pathways: Peptide Hormone Metabolism