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AGRP Protein (AA 83-132, partial) (GST tag)

AGRP Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant 90 % ELISA
Produktnummer ABIN1046485
  • Target Alle AGRP Proteine anzeigen
    AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 83-132, partial
    Spezies
    • 8
    • 4
    • 2
    • 1
    • 1
    Human
    Quelle
    • 6
    • 5
    • 2
    • 2
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses AGRP Protein ist gelabelt mit GST tag.
    Applikation
    ELISA
    Sequenz
    SSRRCVRLHE SCLGQQVPCC DPCATCYCRF FNAFCYCRKL GTAMNPCSRT
    Produktmerkmale
    Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
    Reinheit
    90 %
    Top Product
    Discover our top product AGRP Protein
  • Kommentare

    The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Konzentration
    0.2-2 mg/mL
    Buffer
    Tris-based buffer, 50 % glycerol
    Handhabung
    Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
  • Brown, Mayfield, Volaufova, Argyropoulos: "The gene structure and minimal promoter of the human agouti related protein." in: Gene, Vol. 277, Issue 1-2, pp. 231-8, (2001) (PubMed).

    Shutter, Graham, Kinsey, Scully, Lüthy, Stark: "Hypothalamic expression of ART, a novel gene related to agouti, is up-regulated in obese and diabetic mutant mice." in: Genes & development, Vol. 11, Issue 5, pp. 593-602, (1997) (PubMed).

    Ollmann, Wilson, Yang, Kerns, Chen, Gantz, Barsh: "Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein." in: Science (New York, N.Y.), Vol. 278, Issue 5335, pp. 135-8, (1997) (PubMed).

  • Target
    AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
    Andere Bezeichnung
    Agouti-related protein (AGRP Produkte)
    Synonyme
    AGRT Protein, ART Protein, ASIP2 Protein, Agrt Protein, Art Protein, agouti related neuropeptide Protein, agouti-related protein pseudogene Protein, AGRP Protein, Agrp Protein, LOC100352591 Protein
    Hintergrund
    Plays a role in weight homeostasis. Plays a role in the central control of feeding. Reduces food intake. Inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Acts primarily on MC3R and MC4R. Has very low activity with MC5R By similarity.
    Molekulargewicht
    33.1 kD
    UniProt
    O00253
    Pathways
    Feeding Behaviour, Photoperiodism
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